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Rosie O’Donnell

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PHOTO: L: JIM SPELLMAN/WIREIMAGE.COM / R: SHUTTERSTOCK/DEBBY WONG
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From stand-up comedian to movie actress to daytime television host, the one constant has been O’Donnell’s struggles with her weight, topping out at 240 pounds in 2013. Realizing she wanted to be a healthier role model for her five children, she jump-started her weight loss with a gastric sleeve surgery that helped her shed 75 pounds in two years.

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