42. Hammond, Indiana
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Environmental damage is an issue catching up with a number of US cities, Hammond included. Citizens have started having problems with air and water pollution as well as lead contamination, mainly due to the industrial nature of the town.
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As a result, people have moved onto greener pastures (literally), and the total population has decreased by over 6% in the past decade. Of those remaining in the Indiana city, over 20% live in poverty.
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