Dressed to Kill (1980) 

Dressed to Kill, starring Michael Caine, follows the story of a woman brutally murdered by a cross-dressing serial killer who kills women that turn him on. This movie would likely be lambasted by audiences today. 

While the movie is a classic, the implication is that someone who identifies as the other gender is a killer and would likely get flak online and in Hollywood. This is especially true as in the last few years, society has tried to be extra cautious about anything related to gender identity.